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Thymosin Alpha-1 5mg

Immunomodulatory Research Peptide

$59.00$39.00

Grade: Research Grade / Analytical Standard

Purity: ≥99% (HPLC Verified)

Format: Lyophilized (Freeze-Dried) Powder

Unit Size: 5 mg

Product Overview

Thymosin Alpha-1 5mg (Tα1) is an acidic 28-amino acid peptide naturally produced by the thymus gland. Widely recognized as a primary regulator of adaptive and innate immunity, Thymosin Alpha-1 plays an essential role in modulating T-cell differentiation, enhancing natural killer (NK) cell activity, and restoring immune balance during states of immunosuppression or systemic inflammation.

This 5mg format provides research laboratories with an optimal, highly stable unit for baseline receptor profiling, cytokine expression assays, and cell-mediated immune response studies.

Key Research Features & Highlights

  • Adaptive & Innate Immune Activation: Serves as a primary reference tool for evaluating CD4+ and CD8+ T-cell maturation, dendritic cell activation, and NK cell cytotoxic activity.

  • Toll-Like Receptor (TLR) Signaling: Widely studied for its interaction with TLR2 and TLR9 pathways to trigger intracellular signaling cascades and balanced cytokine release.

  • Immune Homeostasis & Cytokine Balance: Upregulates anti-inflammatory responses while modulating pro-inflammatory cytokine surges in cellular stress models.

  • Analytical Grade Purity (≥99%): Independently validated via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to guarantee high batch-to-batch repeatability.

Primary Applications in Laboratory Research

  • T-Lymphocyte Differentiation & Survival: Investigating thymocyte maturation, T-cell repertoire development, and apoptosis reduction in immune cell cultures.

  • Viral & Pathogen Defense Models: Studying host-directed immune response mechanisms, interferon-gamma (IFN-γ) secretion, and viral replication inhibition in vitro.

  • Immunomodulation in Chronic Stress: Evaluating immune system recovery under conditions of simulated oxidative stress or oncogenic challenge.

  • Vaccine Adjuvant & Synergy Studies: Researching potentiating effects when combined with target antigens or secondary immunomodulators.

Product Specifications

Attribute

Specification

Active Compound

Thymosin Alpha-1 (Tα1 / Thymalfasin)

Net Quantity

5 mg

Form

Lyophilized White Powder

CAS Number

62304-98-7

Molecular Mass

~3108.30 g/mol

Sequence

Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH

Purity Standard

≥99% (HPLC verified)

Solubility

Soluble in Bacteriostatic Water or Sterile Deionized Water

Storage & Handling Protocols

  • Unreconstituted (Lyophilized): Store frozen at or below -20°C in a dry, dark environment protected from heat and UV light exposure.

  • Reconstituted Solution: Maintain at 2°C – 8°C following dilution with sterile solvent (e.g., Bacteriostatic Water) and utilize within 30 days. Avoid repeated freeze-thaw cycles.

Mandatory Research & Legal Disclaimer

FOR LABORATORY RESEARCH USE ONLY. This compound is distributed exclusively for in vitro scientific research, educational, and analytical laboratory application. It is not approved for human or animal consumption, medical therapy, diagnostic procedures, or commercial drug formulation.