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Survodutide 10mg

Dual GLP-1 / Glucagon Receptor Co-Agonist

$100.00$80.00

Grade: Research Grade / Analytical Standard

Purity: ≥99% (HPLC Verified)

Format: Lyophilized (Freeze-Dried) Powder

Unit Size: 10 mg

Product Overview

Survodutide 10mg (BI 456906) is a long-acting synthetic peptide designed for advanced laboratory research into dual-target metabolic regulation. Functioning as a potent co-agonist at both the Glucagon-Like Peptide-1 Receptor (GLP-1R) and the Glucagon Receptor (GCGR), Survodutide integrates incretin-mediated satiety signaling with glucagon-driven energy expenditure and hepatic lipid turnover.

This 10mg high-yield format provides research facilities with an optimal volume for conducting multi-run metabolic assays, liver fat clearance studies, and comparative co-agonist profiling against single-target metabolic mimetics.

Key Research Features & Highlights

  • Dual GLP-1R & GCGR Co-Agonism: Uniquely engages both GLP-1 and glucagon pathways to balance glucose-dependent insulin secretion with increased energy expenditure.

  • Hepatic Lipid Focus: Widely referenced in liver metabolism literature for its ability to target intrahepatic lipid accumulation and metabolic dysfunction-associated steatohepatitis (MASH) models.

  • Engineered Extended Stability: Features a acylated peptide structure optimized for high plasma protein binding, extending plasma half-life during extended analytical protocols.

  • Analytical Grade Purity (≥99%): Independently validated via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to guarantee high batch-to-batch repeatability.

Primary Applications in Laboratory Research

  • Co-Agonist Receptor Kinetics: Investigating differential activation kinetics and cross-talk between GLP-1 and glucagon receptor complexes.

  • Hepatic Steatosis & MASH Research: Analyzing reduction dynamics in liver fat content, fibrotic biomarkers, and intrahepatic lipid turnover.

  • Energy Expenditure & Thermogenesis: Researching energy balance dynamics, mitochondrial oxygen consumption, and basal metabolic acceleration.

  • Glycemic Control & Appetite Mechanics: Studying central satiety pathways alongside glucose-dependent pancreatic hormone dynamics.

Product Specifications

Attribute

Specification

Active Compound

Survodutide (BI 456906)

Net Quantity

10 mg

Form

Lyophilized White Powder

CAS Number

2408821-22-3

Molecular Mass

~3875.40 g/mol

Purity Standard

≥99% (HPLC verified)

Solubility

Soluble in Bacteriostatic Water or Sterile Deionized Water

Storage & Handling Protocols

  • Unreconstituted (Lyophilized): Store frozen at or below -20°C in a dry, dark environment protected from heat and light exposure.

  • Reconstituted Solution: Maintain at 2°C – 8°C following dilution with sterile solvent and utilize within 30 days. Avoid repeated freeze-thaw cycles.

Mandatory Research & Legal Disclaimer

FOR LABORATORY RESEARCH USE ONLY. This compound is supplied strictly for in vitro laboratory research, educational, and analytical evaluation. It is not approved for human or animal consumption, medical therapy, diagnostic procedures, or commercial drug formulation.