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SS-31 (Elamipretide) 10mg

Targeted Mitochondrial Antioxidant Peptide

$70.00$55.00

Grade: Research Grade / Analytical Standard

Purity: ≥99% (HPLC Verified)

Format: Lyophilized (Freeze-Dried) Powder

Unit Size: 10 mg

Product Overview

SS-31 10mg (Elamipretide / Szeto-Schiller-31) is a small, cell-permeable tetrapeptide designed for targeted scientific investigation into mitochondrial bioenergetics and oxidative stress attenuation. Unlike non-specific cellular antioxidants, SS-31 selectively concentrates at the inner mitochondrial membrane (IMM) where it binds directly to cardiolipin, a key phospholipid critical for electron transport chain integrity and ATP production.

This 10mg format provides research laboratories with an optimal volume for conducting precise cellular assays, cardiolipin stabilization studies, and mitochondrial respiration kinetics.

Key Research Features & Highlights

  • Cardiolipin Target Specificity: Selectively interacts with cardiolipin to protect inner mitochondrial membrane structure and optimize electron transport chain efficiency.

  • Mitochondrial ROS Reduction: Inhibits electron leakage at Complex I and Complex III, significantly reducing intracellular Reactive Oxygen Species (ROS) generation at the source.

  • ATP Synthesis Optimization: Restores mitochondrial cristae structure to support ATP production under cellular stress, ischemia, or aging models.

  • Analytical Grade Purity (≥99%): Independently validated via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to guarantee high experimental reproducibility.

Primary Applications in Laboratory Research

  • Mitochondrial Dysfunction & Aging: Investigating bioenergetic rescue in aging, neurodegenerative, and metabolic cell models.

  • Ischemia-Reperfusion Injury: Studying cellular survival pathways, tissue preservation, and oxidative damage reduction during oxygen deprivation assays.

  • Cardioprotective & Renal Research: Analyzing cellular bioenergetics in cardiac myocytes and renal tubular cells exposed to toxic or hypoxic insult.

  • Cardiolipin Structural Biology: Evaluating lipid-protein interactions within the mitochondrial inner membrane during cellular stress.

Product Specifications

Attribute

Specification

Active Compound

SS-31 (Elamipretide / MTP-131)

Net Quantity

10 mg

Form

Lyophilized White Powder

CAS Number

736992-21-2

Molecular Mass

~639.80 g/mol

Sequence

D-Arg-Dmt-Lys-Phe-NH2 (Dmt = 2',6'-dimethyltyrosine)

Purity Standard

≥99% (HPLC verified)

Solubility

Soluble in Bacteriostatic Water or Sterile Deionized Water

Storage & Handling Protocols

  • Unreconstituted (Lyophilized): Store frozen at or below -20°C in a dry, dark environment protected from heat and moisture.

  • Reconstituted Solution: Maintain at 2°C – 8°C following solvent addition and utilize within 30 days to ensure peak chemical stability. Avoid repeated freeze-thaw cycles.

Mandatory Research & Legal Disclaimer

FOR LABORATORY RESEARCH USE ONLY. This compound is distributed exclusively for in vitro scientific research, educational, and analytical laboratory applications. It is not approved for human or animal consumption, medical therapy, diagnostic procedures, or commercial drug formulation.