20% Discount on all orders above $200

Semax 10mg

Heptapeptide Nootropic / Neuroprotective Standard

$50.00$40.00

Grade: Research Grade / Analytical Standard

Purity: ≥99% (HPLC Verified)

Format: Lyophilized (Freeze-Dried) Powder

Unit Size: 10 mg

Product Overview

Semax 10mg (Met-Glu-His-Phe-Pro-Gly-Pro) is a synthetic heptapeptide analogue derived from an ACTH(4-10) fragment. Specifically stabilized with a C-terminal Pro-Gly-Pro tripeptide to resist enzymatic degradation, Semax is widely investigated in neurobiology for its ability to cross the blood-brain barrier and stimulate the expression of key neurotrophic factors, including Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF).

This 10mg format provides research laboratories with a high-purity, stable compound for evaluating synaptic plasticity, cognitive performance, neuroprotective cascades, and cerebral circulation dynamics in central nervous system models.

Key Research Features & Highlights

  • BDNF & NGF Upregulation: Serves as a primary reference tool for analyzing neurotrophin signaling and neurogenesis in hippocampal and cortical cell cultures.

  • Enzymatic Stability (Pro-Gly-Pro sequence): Engineered with a extended peptide tail that prevents rapid peptidase cleavage, extending operational half-life during in vitro assays.

  • Dopaminergic & Cholinergic Modulation: Widely studied for regulating central dopamine and acetylcholine metabolism without activating peripheral adrenocortical axis pathways.

  • Cerebral Protection & Vascular Kinetics: Tailored for evaluating microvascular perfusion, hypoxia tolerance, and cellular survival under ischemic stress.

  • Analytical Grade Purity (≥99%): Independently validated via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to guarantee precise experimental repeatability.

Primary Applications in Laboratory Research

  • Neurotrophic Signaling & Synaptic Plasticity: Investigating BDNF and NGF receptor activation (TrkB/TrkA) and long-term potentiation (LTP) in neuronal networks.

  • Ischemic & Hypoxic Stress Models: Analyzing stroke-mimetic cellular damage, apoptosis reduction, and oxidative stress mitigation in brain tissue cultures.

  • Cognitive Function & Nootropic Mechanisms: Studying memory consolidation, learning retention pathways, and attention performance parameters.

  • Neuroinflammatory Modulation: Evaluating glial cell activation, neuroinflammatory cytokine suppression, and microglial homeostasis.

Product Specifications

Attribute

Specification

Active Compound

Semax

Net Quantity

10 mg

Form

Lyophilized White Powder

CAS Number

80714-61-0

Molecular Mass

~810.90 g/mol

Sequence

Met-Glu-His-Phe-Pro-Gly-Pro

Purity Standard

≥99% (HPLC verified)

Solubility

Soluble in Bacteriostatic Water or Sterile Deionized Water

Storage & Handling Protocols

  • Unreconstituted (Lyophilized): Store frozen at or below -20°C in a dry, dark environment protected from thermal fluctuations and moisture.

  • Reconstituted Solution: Maintain at 2°C – 8°C following dilution with sterile solvent (e.g., Bacteriostatic Water) and utilize within 30 days. Avoid repeated freeze-thaw cycles.

Mandatory Research & Legal Disclaimer

FOR LABORATORY RESEARCH USE ONLY. This compound is distributed exclusively for in vitro scientific research, educational, and analytical laboratory applications. It is not approved for human or animal consumption, medical therapy, diagnostic procedures, or commercial drug formulation.