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Selank 10mg

Heptapeptide Anxiolytic / Immunomodulatory Standard

$65.00$45.00

Grade: Research Grade / Analytical Standard

Purity: ≥99% (HPLC Verified)

Format: Lyophilized (Freeze-Dried) Powder

Unit Size: 10 mg

Product Overview

Selank 10mg (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a synthetic heptapeptide analogue derived from the naturally occurring immunomodulatory tetrapeptide Tuftsin. Stabilized with a C-terminal Pro-Gly-Pro sequence to prevent rapid enzymatic degradation, Selank is widely investigated in neurobiology and immunology for its unique ability to modulate the GABAergic system, inhibit enkephalin-degrading enzymes, and upregulate Brain-Derived Neurotrophic Factor (BDNF) without causing sedating or muscle-relaxant side effects.

This 10mg format provides research laboratories with a high-purity, stable compound for evaluating central nervous system homeostasis, stress-response adaptation, cognitive performance under stress, and neuro-immune cross-talk.

Key Research Features & Highlights

  • GABAergic & Neurotrophic Modulation: Serves as a primary reference tool for analyzing non-sedating GABA receptor allosteric modulation and BDNF expression in hippocampal cell lines.

  • Enzymatic Stability (Pro-Gly-Pro Sequence): Features a C-terminal tripeptide extension engineered to resist peptidase cleavage, extending operational half-life during in vitro assays.

  • Enkephalin Degradation Inhibition: Widely studied for its ability to inhibit enkephalin-degrading peptidases in blood plasma, maintaining endogenous opioid peptide activity under stress.

  • Immunomodulatory Signaling: Tailored for evaluating cytokine balance, interleukin-6 (IL-6) modulation, and T-helper cell signaling in cellular immune models.

  • Analytical Grade Purity (≥99%): Independently validated via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to guarantee precise experimental repeatability.

Primary Applications in Laboratory Research

  • Anxiolytic & Stress Adaptation Pathways: Investigating non-drowsy stress-response mitigation, corticotropin-releasing factor (CRF) inhibition, and behavioral adaptation models.

  • Cognitive Plasticity & Memory Consolidation: Studying BDNF/TrkB signaling cascades, synaptic plasticity, and memory retention under environmental stress conditions.

  • Neuroinflammatory & Immune Interactions: Evaluating microglial homeostasis, neuro-immune cross-talk, and peripheral immune cell recruitment.

  • Neurotransmitter Metabolism: Analyzing monoamine (dopamine, serotonin) turnover rates in central nervous system structures.

Product Specifications

Attribute

Specification

Active Compound

Selank

Net Quantity

10 mg

Form

Lyophilized White Powder

CAS Number

129954-34-3

Molecular Mass

~751.90 g/mol

Sequence

Thr-Lys-Pro-Arg-Pro-Gly-Pro

Purity Standard

≥99% (HPLC verified)

Solubility

Soluble in Bacteriostatic Water or Sterile Deionized Water

Storage & Handling Protocols

  • Unreconstituted (Lyophilized): Store frozen at or below -20°C in a dry, dark environment protected from thermal fluctuations and moisture.

  • Reconstituted Solution: Maintain at 2°C – 8°C following dilution with sterile solvent (e.g., Bacteriostatic Water) and utilize within 30 days. Avoid repeated freeze-thaw cycles.

Mandatory Research & Legal Disclaimer

FOR LABORATORY RESEARCH USE ONLY. This compound is distributed exclusively for in vitro scientific research, educational, and analytical laboratory applications. It is not approved for human or animal consumption, medical therapy, diagnostic procedures, or commercial drug formulation.