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Ipamorelin 10mg

High-Yield Selective GHRP / Somatotroph Secretagogue Standard

$65.00$45.00

Grade: Research Grade / Analytical Standard

Purity: ≥99% (HPLC Verified)

Format: Lyophilized (Freeze-Dried) Powder

Unit Size: 10 mg

Product Overview

Ipamorelin 10mg (Aib-His-D-2Nal-D-Phe-Lys-NH2) is a synthetic pentapeptide Growth Hormone Secretagogue (GHS) and selective agonist at the Growth Hormone Secretagogue Receptor (GHS-R1a / Ghrelin Receptor). Renowned in neuroendocrine literature for its exceptional selectivity, Ipamorelin stimulates the pituitary gland to release endogenous growth hormone (GH) without triggering secondary increases in plasma cortisol, prolactin, aldosterone, or appetite-stimulating pathways typical of earlier-generation GHRPs (such as GHRP-2 or GHRP-6).

This high-yield 10mg format provides research facilities with a cost-effective, high-capacity unit ideal for extended cellular assays, multi-run pulsatile GH kinetic trials, and comparative receptor-selectivity studies.

Key Research Features & Highlights

  • High Receptor Selectivity: Binds specifically to GHS-R1a, triggering clean somatotrophic bursts without elevating baseline cortisol or prolactin levels.

  • Bulk 10mg Capacity: Maximizes experimental throughput and protocol continuity for long-term cell culture studies and multi-dose testing runs.

  • Pulsatile Secretion Kinetics: Delivers brief, high-amplitude growth hormone release pulses that mimic natural physiological pituitary secretion dynamics.

  • Downstream IGF-1 Axis Upregulation: Serves as a primary reference tool for evaluating systemic Insulin-like Growth Factor 1 elevation, cellular protein translation, and nitrogen retention.

  • Analytical Grade Purity (≥99%): Independently validated via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure baseline consistency and batch reproducibility.

Primary Applications in Laboratory Research

  • Pituitary GHS-R1a Activation: Investigating selective ghrelin receptor signaling, intracellular calcium ion flux, and somatotroph secretagogue pathways.

  • Protein Translation & Muscle Hypertrophy: Researching Akt/mTOR cascade upregulation, satellite cell activation, and nitrogen retention dynamics in muscle models.

  • Bone Mineral Density & ECM Remodeling: Studying osteoblast differentiation, chondrocyte expansion, and Type I collagen synthesis in connective tissues.

  • Adipocyte Lipolysis & Metabolic Regulation: Evaluating lipid clearance mechanisms, free fatty acid oxidation, and basal metabolic rate acceleration.

Product Specifications

Attribute

Specification

Active Compound

Ipamorelin

Net Quantity

10 mg

Form

Lyophilized White Powder

CAS Number

170851-70-4

Molecular Mass

~711.86 g/mol

Sequence

Aib-His-D-2Nal-D-Phe-Lys-NH2

Purity Standard

≥99% (HPLC verified)

Solubility

Soluble in Bacteriostatic Water or Sterile Deionized Water

Storage & Handling Protocols

  • Unreconstituted (Lyophilized): Store frozen at or below -20°C in a dry, dark environment protected from heat, light, and thermal fluctuations.

  • Reconstituted Solution: Maintain at 2°C – 8°C following dilution with sterile solvent (e.g., Bacteriostatic Water) and utilize within 30 days. Avoid repeated freeze-thaw cycles.

Mandatory Research & Legal Disclaimer

FOR LABORATORY RESEARCH USE ONLY. This compound is distributed exclusively for in vitro scientific research, educational, and analytical laboratory applications. It is not approved for human or animal consumption, medical therapy, diagnostic procedures, or commercial drug formulation.